Analysis of the Internal Structure of Peripheral Pulmonary Lesions Using Endobronchial Ultrasonography

Analysis of the Internal Structure of Peripheral Pulmonary Lesions Using Endobronchial UltrasonographyNumerous reports have shown that high’ frequency, two-dimensional ultrasonography is a useful technique for evaluating the depth of invasion of gastrointestinal tumors, for detecting lymph node metastasis, and for identifying coronary stenosis and thrombosis. Since 1994, our facility has worked on the development of endobronchial ultrasonography (EBUS). EBUS uses a miniature probe inserted through the working channel of a flexible bronchoscope to scan the bronchial lumen. The procedure is able to accomplish the following: (1) determine the depth of invasion in cases of tracheobronchial lesions-; (2) check for invasion of the pulmonaryarter-ies and veins by hilar tumors, and identify lesions and distinguish metastasis to paratracheal and parabron-chial lymph nodes”; and (3) localizeperipheral pulmonary lesions during endobronchial brushing and transbronchial biopsy (TBB) Click Here canadian pharmacy mall. The present study was undertaken to examine the internal structure of peripheral pulmonary lesions as visualized by EBUS and to correlate these findings with the histopathology. The goal was to improve the criteria for distinguishing between benign and malignant peripheral pulmonary tumors.
Materials and Methods

Correlation Between Preoperative EBUS Images and the Histopathology of Peripheral Pulmonary Lesions: The records of 69 patients who underwent diagnostic preoperative EBUS for a peripheral lesion between January 1996 and December 2000 and whose surgical specimens could be sectioned were reviewed. The histopathologic findings were correlated with the internal structure of the lesions, as visualized by EBUS.
Typing the Internal Structure of 124 Lesions Visualized by EBUS: One hundred sixty-eight patients with peripheral pulmonary lesions underwent EBUS between January 1997 and December 2000, and EBUS was able to visualize the lesion in 143 patients (85.1%). Of these patients, a definitive histopathologic diagnosis was made in 124 (73.8%). The internal structure of these lesions was analyzed, and the lesions were typed based on these findings.