Bronchoalveolar Lavage in Liquid Paraffin Pneumonitis: Results (3)

BALF Cell Populations in Liquid Paraffin Pneumonitis
The BALF recovered from the seven patients with liquid paraffin pneumonitis was whitish and turbid with many oil droplets on the surface. The percentage of recovery was greater than 40 percent of the injected fluid for the seven patients (Table 2). ventolin inhalers
The mean total cell count in the BALF from these seven patients was not significantly increased as compared to the nonsmoker control subjects (respectively [25.5 ±15.8] x 106 vs [20.3 ±6.1] x 106, p>0.1) (Table 2). However, the distribution of the cell populations was modified in mineral oil pneumonitis. There was a large decrease in the mean AM number and percentage as compared to the control group ([9.6±3.8] x 106 vs [18.2±6] x 10″, p<0.01; and 46.6 ±21.9 percent vs 89.7 ±6.5, p<0.001 respectively). The mean neutrophil count (10.7 ± 11.3) x 106 and percentage (32.7 ±21.1 percent) of the patient group were increased as compared to the mean control number (0.42 ±0.32) X 10s, p<0.02 and percentage (2.3 ±1.8 percent). The lymphocyte and eosinophil numbers were also significantly higher in the patient BALF, but not at a level as high as that of neutrophils.

Table 2—Numbers and Types of Cells Recovered in the Bronchoalveolar Lavage Fluid of Patients with Liquid Paraffin Pneumonitis and Ten Control Subjects

PercentRecovery

Fluid

Total Cells x ltf* Macrophages Lymphocytes Neutrophils Eosinophils
Patient x 10 % x 10 % X ltf’ % x 10 %
1 60 30 8.7 29 4.8 16 15.3 51 1.2 4
2 47 22 12.3 56 1.1 5 7.5 34 1.1 5
3 60 17 10.2 60 3.4 20 2.7 16 0.68 4
4 44 56 11.2 20 7.8 14 32.5 .58 4.5 8
5 42 20 14.6 73 4.0 20 1.4 7 0 0
6 53 29 6.8 23 7.1 24 15.1 51 0 0
7 40 4.8 3.1 65 0.5 11 0.6 12 0.5 12
Mean± SD 49.4 ± 8.3t 25.5 ±15.8 9.6±3.8t 46.6±21.9t 4.1 ±2.8* 15. 7 ±6.4* 10.7 ±11* 32.7 ± 211 1.1 ± 1.5* 4.7 ±4.3t
Normal volunteers N = 10 73.5 ±12 20.3 ±6.1 18.2±6.0 89.7 ±6.5 1.6± 1.4 8 ±6.5 .4 ±.3 2.3± 1.8 0 0
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