Archive for the ‘Asthma and Chronic Airflow Limitation’ Category - Part 2

Individualized Aerobic and High Intensity Training for Asthmatic Children (6)

During one aerobic training session, the children swam for 10 min, three times at their own VTh velocity (individualized training). The children were aware of their velocity by being informed of their swimming time every 25 m. It was thus possible for them to control their swimming speed. The duration of one session was one […]

Individualized Aerobic and High Intensity Training for Asthmatic Children (5)

The reading was effected independently by two observers. In the rare case of discordance, a third one was used to reach a consensus or to eliminate the subject (in this study a consensus was always reached). ampicillin antibiotic The maximal oxygen pulse (Vo2max/H Rmax) was expressed in ml.kg’, beat. Protocol The subjects were tested before […]

Individualized Aerobic and High Intensity Training for Asthmatic Children (4)

Each gas analyzer was calibrated before and after each test with standard gases. The inspiratory airflow and the fractions of expired Og and CO* (Fe02 and FeCOJ were calculated by a computer from ten breath cycles. Averages were established for minute ventilation (Ve L.min _l BTPS), Ot uptake (Vo2 L.min _1 STPD), CO* production (Vco2 […]

Individualized Aerobic and High Intensity Training for Asthmatic Children (3)

Measurements The maximum expiratory flow-volume curves were performed on a digital spirometer (Datalink pulmochart). The lung function study included FVC, FEV,, maximal expiratory flow at 50 percent of FVC, and forced expiratory flow between 25 and 75 percent of FVC. The following values were then calculated: FEV,/FVC and FEF25-75/FVC. The predicted values were those of […]

Individualized Aerobic and High Intensity Training for Asthmatic Children (2)

Material and Methods Subjects This study was carried out with 14 atopic asthmatic children, during a six-month period. All the asthmatic subjects were known to have had recurrent reversible wheezing episodes and were required to fulfill at least three of the four following criteria: (1) clinical: family history of asthma and/or personal history of eczema, […]

Individualized Aerobic and High Intensity Training for Asthmatic Children (1)

In spite of the aerobic fitness limitation described in asthmatic children, there are surprisingly few studies on the retraining of these patients. In the earliest studies, attention was focused on the asthmogenic character of various sports. According to subsequent studies, there was some evidence that if the levels of ventilation and inspired air conditions were […]

Management of Asthma and Chronic Airflow Limitation: Conclusion

Theophylline has for decades been considered first-line therapy for acute exacerbations and for the maintenance treatment of asthma and COPD. This review presents evidence which suggests that theophylline offers little additional benefit to dose-optimized aerosol bronchodilators in the management of patients with acute exacerbations of asthma and COPD and in the maintenance therapy of asthma […]

Management of Asthma and Chronic Airflow Limitation (Part 15)

A recent study illustrates the potential for serious toxicity from therapeutic misadventure with this drug. In a prospective four-month surveillance of potentially toxic theophylline levels in hospitalized patients at a major university hospital, 44 episodes in 39 patients were studied. In all of the patients, serum theophylline levels were over 20 |xg/ml (mean, 28 mg/ […]

Management of Asthma and Chronic Airflow Limitation (Part 14)

Investigators have reported drug interactions with theophylline with increasing frequency. Indeed, the recently introduced quinolone antibiotics such as norfloxacin and ciprofloxacin have been associated with at least one death attributed to theophylline toxicity. Calcium channel blockers are other commonly used drugs that may have profound effects on theophylline clearance. Common non-life-threatening side effects of theophylline […]

Management of Asthma and Chronic Airflow Limitation (Part 13)

Overall, the literature does not support the almost universal North American and Japanese practice of prescribing theophylline to virtually all patients with chronic airflow obstruction. Cautious and carefully monitored addition of theophylline to the therapeutic regimen should be considered only after the dose of aerosol betas adrenergic and/or anticholinergic agents has been maximized. To establish […]

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