Seventy-seven percent of the patients with sarcoidosis were symptomatic by questionnaire at the time of the study (Table 1). Symptoms included exertional dyspnea in 23, easy fatigability in eight, and palpitations in two. Thirteen patients had stage 1 chest roentgenograms, 14 had stage 2 chest roentgenograms, and eight had stage 3 chest roentgenograms. Nineteen had […]
Archive for the ‘Cardiac Dysfunction’ Category - Part 2
Radionuclide Equilibrium Angiography To investigate whether abnormal exercise HR responses in patients without evident cardiac sarcoidosis were related to impaired ventricular contractility, left ventricular ejection fraction (LVEF) was measured by gated equilibrium radionuclide angiography (RNA) performed at rest. This technique was used to evaluate ventricular performance in 28 patients and 18 normal controls. The method […]
End-tidal carbon dioxide and oxygen tension, carbon dioxide production (VcoJ, oxygen consumption (VoJ, minute ventilation (Ve), tidal volume, and respiratory rate were measured continuously throughout exercise. Air flow and gas measurements were corrected for ambient temperature, barometric pressure, water vapor, and expressed in body temperature pressure saturated (BTPS). Peak exercise values of Vo2 were expressed […]
Analysis of the tapes was performed by one of us (IM) using a high-speed analyzer (Reynolds Pathfinder) equipped with a printer interface module to allow printouts of the hourly totals of all QRS complexes, premature aberrant beats, pairs, and salvoes of >3 premature ventricular complexes, premature supraventricular beats, and hourly maximum and minimum HRs. The […]
Roentgenographic Staging All 35 patients with sarcoidosis had posterior-anterior and lateral chest roentgenograms. Roentgenographic stage was defined as (1) bilateral hilar adenopathy alone, (2) bilateral hilar adenopathy plus parenchymal infiltrates, and (3) parenchymal infiltrates alone without hilar adenopathy.
Subjects and Methods Subject Selection Thirty-eight sequential patients were referred to our Respiratory Division with a diagnosis of pulmonary sarcoidosis during the 18-month period of the study. Three patients were excluded from the study because of the presence of one or more of the following exclusion criteria: presence of lung disease other than sarcoidosis, the […]
Sarcoidosis is a clinical disorder of unknown cause, characterized by granulomatous infiltration of the lungs and other organs. In the heart, noncaseating granulomata can involve the ventricular septum, papillary muscles, and/or free ventricular walls in up to 30 percent of cases at autopsy. However, a discrepancy between clinical and autopsy finding exists, since only about […]