Archive for the ‘Intrahepatic cholangiocarcinoma’ Category

Well-differentiated intrahepatic cholangiocarcinoma in the setting of biliary papillomatosis: DISCUSSION (Part 2)

The pathogenesis of the disease is not yet known, but has been thought to be related to chronic biliary ductal inflammation from pancreatic juice reflux, biliary infection or stone disease . The resulting inflammation and duct dilation induces overproliferation of the bile duct epithelium followed by the dysplasia-carcinoma sequence. The obstruction is thought to be […]

Well-differentiated intrahepatic cholangiocarcinoma in the setting of biliary papillomatosis: DISCUSSION (Part 1)

BP is rare neoplasm first described by Caroli in 1959 . To date, there are fewer than 100 cases reported in the English literature. BP has a 2:1 male to female ratio, and mean age at presentation is the seventh decade of life (60 to 70 years of age). Initially, BP was thought to be […]

Well-differentiated intrahepatic cholangiocarcinoma in the setting of biliary papillomatosis: CASE PRESENTATION (Part 2)

At laparotomy, the tumour was soft and fleshy, making it difficult to palpate the margins of the lesions. Intraoperative ultrasound was therefore important for defining the extent of resection. The patient underwent an uncomplicated left hepa-tectomy (segments 2, 3 and 4) and made an uneventful recovery.

Well-differentiated intrahepatic cholangiocarcinoma in the setting of biliary papillomatosis: CASE PRESENTATION (Part 1)

A 64-year-old man was investigated for long-standing, vague, epigastric abdominal pain. His pain had a recurring and relapsing time course. He had a history of peptic ulcer disease, hypertension and insulin-dependent , and he had undergone a laparoscopic cholecystectomy in the previous year. The patient had no history of jaundice, liver disease, hepatitis or alcohol […]

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