Category: Intrahepatic cholangiocarcinoma

Well-differentiated intrahepatic cholangiocarcinoma in the setting of biliary papillomatosis: DISCUSSION (Part 2)

Well-differentiated intrahepatic cholangiocarcinoma in the setting of biliary papillomatosis: DISCUSSION (Part 2)

The pathogenesis of the disease is not yet known, but has been thought to be related to chronic biliary ductal inflammation from pancreatic juice reflux, biliary infection or stone disease . The resulting inflammation and duct dilation induces overproliferation of the bile duct epithelium followed by the dysplasia-carcinoma sequence. The obstruction is thought to be due to mucous secretion or the enlarging papilloma. Treatment for…

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Well-differentiated intrahepatic cholangiocarcinoma in the setting of biliary papillomatosis: CASE PRESENTATION (Part 1)

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A 64-year-old man was investigated for long-standing, vague, epigastric abdominal pain. His pain had a recurring and relapsing time course. He had a history of peptic ulcer disease, hypertension and insulin-dependent , and he had undergone a laparoscopic cholecystectomy in the previous year. The patient had no history of jaundice, liver disease, hepatitis or alcohol abuse. His physical examination was normal. He was investigated with…

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