Droplets Produced by Medical Nebulizers: Results (Part 2)

The ultrasonic nebulizer solution output is much larger than that of the jet nebulizers. The output vs time graph is shown in Figure 4. The output without tubing or valve was found to be approximately constant at 4.8 ml/min over the time period tested. The output through the two-way valve was found to be greatly reduced and was dependent on the flow rate of the aerosol through it (Fig 4).
The change in concentration of solution in the nebulized aerosol droplets can be seen for each nebulizer system in Figure 5. The solute concentration contained in the aerosol produced by the jet nebulizers increases significantly with the fall in nebulizer temperature and with the reduction in the dilution air humidity. At the steady temperature Ts the droplet solution reaches 5.8 and 9.2 percent sodium chloride for the Cadema and Up-Draft nebulizers, respectively, mately 13 min.The droplet size distributions of the jet-nebulizer using 8 L/min of compressed oxygen as the generation gas. The Flatus/Up-Draft system reaches a little less than 5 percent and the Aerosol-One/Up-Draft reaches approximately 36 percent saline solution after the same generation time. buy levaquin online


Figure 4. Graph of output vs generation time for the Mist-02-Gen ultrasonic nebulizer: no tubing or valve (circles), Bennett tubing and valve (model 2700, Hans Rudolf Inc., Kansas City, MO) attached; 10 L/min flow rate (triangles), 20 L/min (squares), 30 L/ min (diamonds) and 50 L/min (crosses).


Figure 5. Graph of droplet solute concentration (solid symbols, % W/V) and mass median aerodynamic diameter (open symbols, p-m) vs nebulizer solution temperature for the four jet-nebulizer systems: Up-Draft/Aerosol-One (squares), Up-Draft/Flatus (diamonds), Cadema/compressed oxygen (circles) and Up-Draft/compressed oxygen (triangles). Note that the ambient temperature is the highest value on each graph.