Elevated Pulmonary Artery Pressure: Discussion (Part 6)
The finding that PAMP correlates positively with aortic mean pressure and LV mass suggests that a stimulus raising vascular tone affects both the pulmonary circulation and the systemic circulation. Overresponsiveness of pressures in both vascular beds has been shown to occur with both adrenergic stimuli and exercise in hypertensive patients,- and there is evidence that in systemic hypertension with LVH, there is an elevation of MPAP whose degree is proportional to the severity of hypertension. buy birth control online
In summary, our data indicate a strong association between PAMP and mortality in patients followed up after cardiac catheterization. This relationship is independent of LV systolic function, the status of the coronary arteries, and the severity of LVH. It also points to the powerful interaction between increased pulmonary pressure and LVH. These data strongly suggest that measures of pulmonary artery pressure are reflecting LV diastolic dysfunction and provide for the first time prospective data on the mortality risk associated with this form of myocardial abnormality.