Gastric emptying scintigraphy: Prevalence of lower bowel dysfunction (Part 1)

Autonomic dysfunction is frequently observed in patients with MS, but clinical studies have shown contradictory findings regarding the frequency and type of abnormalities in autonomic function tests. In the present study, the gastric emptying rate was prolonged in MS patients compared with controls, as evidenced by the longer mean half-time in the former (P<0.05). This was consistent with the reports that document gastric dysfunction in patients with MS who presented with symptoms of delayed gastric emptying. The complaints reported were mainly a sense of fullness, nausea and persistent vomiting, recurrent hiccups and gastroesophageal reflux. The prevalence of lower bowel dysfunction in patients with MS is much higher and has been reported to range from 41% to 68% in different studies. In the present study, the symptoms of bowel dysfunction encountered were mainly constipation, in approximately 59% of patients, and fecal incontinence, either alone or in association with constipation, in approximately 36%. Many studies are in agreement with these findings. Best quality drugs cheap: find and discover best deals online.

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