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The mean half-time was greater in patients with constipation (64.4±23.2 min); nevertheless, there was no statistically significant difference between patients with constipation and patients without constipation (P=0.197). Moreover, although the mean half-time was lower in patients with fecal incontinence (49.9±16.8 min), there was no statistically significant difference when compared with those without fecal incontinence (P=0.654) (Table 1).
Gastric emptying half-time and MRI findings
Separate analysis for the half-time values according to the site of plaques in the MRI was carried out. There was no significant difference in the mean half-time between different patient subgroups with periventricular, centrum semiovale, corpus callosum, cerebellar, brainstem or spinal cord plaques (P>0.05 for all).
TABLE 1 Half-time (T1/2) rate of gastric emptying in the subgroups of multiple sclerosis (MS) patients included in the present work
|Variable||T1/2 (mean ± SD)||P|
|MS patients with constipation||64.4±23.2||0.197|
|MS patients without constipation||51.4±20.2||0.197|
|MS patients with fecal incontinence||49.9±16.8||0.654|
|MS patients without fecal incontinence||69.4±34.8||0.654|