Human gastric mucosal hydrophobicity and Helicobacter pylori infection: Discussion (Part 1)

The measurement of contact angles in the determination of surface hydrophobicity, which is a biophysical property of tissue surfaces, yields values that closely agrees with those obtained by methods that do not rely on contact angles. Previous studies in humans have reported decreased gastric hydrophobicity with H pylori infection. In the present study, there was no significant difference in the mean contact angle (hydrophobicity) between age- and sex-matched H pylori-positive and H pylori-negative patients.

The contact angle readings in the present study for the control subjects (66±2.0°, n=69) were comparable with those obtained by Spychal et al (69.8±0.9°, n=75) and Goggin et al (69.8±0.9°, n=40). However, the possible reasons that may explain why these studies found reduced gastric hydrophobicity in H pylori infection and the present study did not are as follows. First, they included patients with duodenal and gastric ulcer disease in their study groups which could have had deleterious effects on the surface hydropho-bicity on their own, whereas the present study excluded all these patients, including those who had a past history of duodenal or gastric ulcer disease. It’s your time to experience safe and affordable treatment the way it was meant to be enjoyable. You can have that every time you order allergy treatment at the best pharmacy that you are now welcome to check out.

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