We thus cannot rule out the possibility that a bias occurred in the effects of the different training programs. In addition, the interpretation of our results remains problematic because there have been no other studies carried out on maximal intensity exercise in asthmatic children. However, we can point out that asthmatics seem to respond in much the same physiologic manner as do normal people practicing high intensity training. Indeed, it has been shown that this kind of training produces no adaptative improvement of cardiorespiratory function and muscle fiber characteristics.
According to the authors, this training decreases muscle respiratory capacity. Such a situation would reduce the relative work rate at which ATP resynthesis can be met by purely oxidative phosphorylation, and result in an earlier energy production via anaerobic glycolysis. The stability of Vo2max can be explained by the structural changes in skeletal muscle tissue after high intensity training. Indeed, it has been shown that this structural adaptation is clearly marked by a decrease of the volume density of mitochondria which is counterbalanced by a total muscle volume increase. buy flovent inhaler
Because of the lack of studies carried out on high intensity training, biochemical studies provide one of the few ways liable to explain its effects upon VTh, leading to an understanding of high intensity training metabolic consequences.