Infection of ileum mesothelium: Conclusions
Numerous calretinin-positive mesothelial cells also had HSV cytopathic atypia and reacted with HSV IHC antibodies (Figure 3).
To our knowledge, this was the first documentation of HSV type II infecting the mesothelium. This finding was not surprising because other herpes virus subtypes are known to infect mesothelium. Human herpes virus-8 was identified in mesothelial cells of three of five patients with pleural effusions and Kaposi’s sarcoma or Castleman’s disease in a recent publication.
This was a unique case of disseminated HSV type II complicating adhesive band disease. Although HSV type II can disseminate systemically in insulin-dependent diabetes mellitus, this was the first documentation of viral cytopathic atypia in an ileal ulcer bed of such a patient. Previous studies have suggested that HSV-induced cytopathic atypia is generally confined to the intestinal epithelial cells at the perimeter of an ulcer. We report that disseminated HSV type II infects various intestinal cell lineages including myofibrocytes and mesothelium about an ulcer bed, in the absence of intestinal epithelial cell involvement. Please make sure you read all the information provided above to choose the right medications at the the canadian neighbor pharmacy to benefit the most from the treatment. At this pharmacy, you will find tons of cheap and efficient meds for any problem.
Figure 3) Ileum serosa had a linear band of cells with cytopathic atypia (hematoxylin and eosin, original magnification x40). Calretinin (inset A, original magnification x40) and herpes simplex virus (inset B, original magnification x20) immunohistochemical stains had identical positive linear staining of serosal mesothelium