Medroxyprogesterone Acetate: RESULTS(5)

RESULTS(5)

There was a significant difference between the treated and control ewes in terms of progesterone concentrations after ovulation following MAP treatment in treated ewes. The treated ewes exceeded control ewes in mean serum concentrations of progesterone on Day 4 (1.49 ± 0.33 vs. 1.03 ± 0.22 ng/ml) and Day 5 (2.41 ± 0.29 vs. 1.32 ± 0.25 ng/ml) after ovulation (treated vs. control ewes, respectively, P < 0.05). allergy relief

Serum concentrations of gonadotropins and estradiol. The main effect of group (P = 0.68), day (P = 0.89), and interaction (P = 0.33) were not significant for daily serum concentrations of FSH for the period from 1 day before to 1 day after MAP treatment of treated ewes. Circulating concentrations of estradiol in the ewes of the present study differed by day (P < 0.001), but there was no significant effect of treatment (P = 0.60) and interaction of the main effects was not significant (P = 0.29). Mean daily concentrations of FSH and estradiol did not vary between the two groups during the period from 3 days before to 5 days after ovulation following MAP treatment (P > 0.05).

The secretory parameters of FSH and LH in the present ewes, based on the intensive blood sampling, were not affected by the treatment with PGF2a and MAP. The mean serum concentrations of FSH did not differ between groups (1.32 ± 0.16 and 1.53 ± 0.26 ng/ml for treated and control ewes, respectively; P > 0.05). Mean and basal levels of LH, LH pulse frequency, amplitude, and duration were 0.20 ± 0.02 and 0.20 ± 0.03 ng/ml, 0.13 ± 0.02 and 0.15 ± 0.01 ng/ml, 0.29 ± 0.09 and 0.27 ± 0.07 pulse/h (range, zero to three pulses per 6 h in both treated and control ewes); 0.47 ± 0.10 and 0.47 ± 0.12 ng/ml; and 54 ± 15 and 48 ± 11 min; for treated and control ewes, respectively (P > 0.05).

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