Prognostic Value off Bronchoalveolar Lavage Lymphocyte Count in Recently Diagnosed Pulmonary Sarcoidosis (3)
Pulmonary (unction parameters tested were total lung capacity (TIXJ), forced vital capacity (FVC), forced expiratory volume in one second (FEVJ, functional residual capacity (FRC) (plethysmography), and diffusing capacity with the single-breath carbon monoxide method (Deo). These parameters were measured as previously described and expressed as a percentage of predicted values. buy yasmin online
BAL and Lavage Fluid Processing
BAL was performed during flexible bronchoscopy with the patient under local anesthesia as previously described. A segment or a subsegment of the right middle lobe or another lobe was lavaged. When there was an asymmetric distribution of lung infiltrates, lavage fluid was obtained from the region with the predominant infiltration. Five 20-ml aliquots (n = 57) or four boluses of 50 ml of 0.9 percent saline solution (n = 41) were instilled and withdrawn by gentle aspiration with a syringe. The total cell count was determined on a hemocytometer. The cell differential was obtained by counting at least 300 cells on both Wright-Giemsa and nonspecific esterase-stained cytocentrifuge preparations. Recovery of less than 35 percent of the instilled volume was considered an inadequate return, and these results were discarded. A percentage of BAL lymphocytes ^30 percent was considered to respresent high-intensity alveolitis; a lymphocyte count <30 percent, low-intensity alveolitis.