Prognostic Value off Bronchoalveolar Lavage Lymphocyte Count in Recently Diagnosed Pulmonary Sarcoidosis (5)
Adjusted means were estimated by covariance analysis and tested with an F statistic. Residuals were examined to verify the normality assumption. In the treated group, the predictive value of BAL lymphocyte count for the responsiveness to steroid treatment was evaluated by correlating the variation of pulmonary functions before and during treatment to the initial BAL lymphocyte percent (Spearmans correlation coefficient). buy ventolin inhalers
The 98 subjects included in the current analysis included 50 men and 48 women aged 17 to 69 years (mean, 37.4 years). All were white. Sixty had never smoked, 15 had stopped smoking for more than ten months (mean ± SD, 59.7 ±45.7 months), and 15 were smokers (mean usage, 17.7 ±8.9 pack-years). The patients were followed up for a mean period of 25.6 months (range, 6 to 60 months). Histologic confirmation (presence of sarcoid granuloma on biopsy) was obtained in 48 subjects (49 percent). Transbronchial biopsies were performed in 76 subjects, and nonca-seating granuloma was seen in 38 patients (50 percent). Mediastinoscopy, peripheral lymph node biopsy, and salivary gland biopsy showed histologic findings compatible with sarcoidosis in 7, 1, and 2 patients, respectively. Three subjects had a normal lung roentgenogram (stage 0), 39 had hilar adenopathies (stage 1), 41 had both adenopathies and pulmonary infiltrates (stage 2), and 15 had pulmonary infiltrates alone (stage 3).